Safety Profile (Research Context)
Semaglutide has been extensively studied in clinical research settings and is generally well tolerated. Reported side effects are most commonly gastrointestinal in nature and tend to occur during the initiation and dose-escalation phases. These effects are typically mild to moderate and often diminish as the body adapts. Long-term studies continue to monitor safety parameters, including metabolic, gastrointestinal, and cardiovascular markers, to further establish its tolerability profile.